regex - 使用 tidyr 从列中提取值

Question

我将 data.frame annot 定义为:

annot <- structure(list(Name = c("dd_1", "dd_2", "dd_3","dd_4", "dd_5", "dd_6","dd_7"), GOs = 
c("C:extracellular space; C:cell body; P:cell migration process; P:NF/ß pathway", 
   "C:Signal transduction; C:nucleus; F:positive regulation; P:single organism; P:positive(+) regulation",
   "C:cardiomyceltes; C:intracellular pace; F:putative; F:magnesium ion binding; F:calcium ion binding; P:visual perception; P:blood coagulation",
   "F:poly(A) RNA binding; P:DNA-templated transcription, initiation",
    "C:ULK1-ATG13-FIP200 complex; F:histone-arginine N-methyltransferase activity; P:single-organism cellular process",
    "F:3'-5' DNA helicase activity; P:acetate-CoA ligase activity",
    "F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; P:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"
)), .Names = c("Name", "GOs"), class = "data.frame", row.names = c(NA, 
-7L))

data.frame 如下所示:

Name     GOs
dd_1     C:extracellular space; C:cell body; P:cell migration process; P:NF/ß pathway 
dd_2     C:Signal transduction; C:nucleus; F:positive regulation; P:single organism; P:positive(+) regulation
dd_3     C:cardiomyceltes; C:intracellular pace; F:putative; F:magnesium ion binding; F:calcium ion binding; P:visual perception; P:blood coagulation
dd_4     F:poly(A) RNA binding; P:DNA-templated transcription, initiation
dd_5     C:ULK1-ATG13-FIP200 complex; F:histone-arginine N-methyltransferase activity; P:single-organism cellular process
dd_6     F:3'-5' DNA helicase activity; P:acetate-CoA ligase activity
dd_7     F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; P:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

每个条目都包含 C、F、P 中的单词、特殊字符、字母数字字符。我想拆分与 C:xxx;F:yyy:P:zzz 对应的所有值将其对应的值分成单独的列，如下所示:

Name   Component                             Function                  P
dd_1   C:extracellular space;C:cell body     F:transport carrier       P:cell migration process;P:NF/ß pathway  
dd_2   C:Signal transduction;C:nucleus       F:positive regulation     P:single organism;P:positive regulation 
dd_3   C:cardiomyceltes;C:intracellular pace F:magnesium ion           P:visual perception;P:blood coagulationbinding;F:calcium ion binding; 
dd_4                                         F:poly(A) RNA binding;    P:DNA-templated transcription, initiation
dd_5   C:ULK1-ATG13-FIP200 complex           F:histone-arginine N-methyltransferase activity               P:single-organism cellular process
dd_6                                         F:3'-5' DNA helicase activity; P:acetate-CoA ligase activity
dd_7                                         F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity P:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

我尝试使用 tidyr 在 R 中执行以下命令

separate(annot, GOs, into = c("P", "F", "C"), sep = "[a-z]+=")

但它返回了以下错误:

Error: Values not split into 3 pieces at 1, 2, 3,4

Answer 1

我认为你最好使用这样的整洁格式:

library(tidyr)
library(dplyr)
annot %>%
  tbl_df() %>%
  mutate(GOs = strsplit(GOs, "; ")) %>% # split each GO into a vector
  unnest(GOs) %>%  # unnest the vectors into multiple rows
  separate(GOs, c("type", "value"), ":") 
#> Source: local data frame [25 x 3]
#> 
#>    Name type                  value
#> 1  dd_1    C    extracellular space
#> 2  dd_1    C              cell body
#> 3  dd_1    P cell migration process
#> 4  dd_1    P           NF/ß pathway
#> 5  dd_2    C    Signal transduction
#> 6  dd_2    C                nucleus
#> 7  dd_2    F    positive regulation
#> 8  dd_2    P        single organism
#> 9  dd_2    P positive(+) regulation
#> 10 dd_3    C         cardiomyceltes
#> ..  ...  ...                    ...